Neanderthal DNA yields to genome foray
نویسندگان
چکیده
منابع مشابه
Sequencing and analysis of Neanderthal genomic DNA.
Our knowledge of Neanderthals is based on a limited number of remains and artifacts from which we must make inferences about their biology, behavior, and relationship to ourselves. Here, we describe the characterization of these extinct hominids from a new perspective, based on the development of a Neanderthal metagenomic library and its high-throughput sequencing and analysis. Several lines of...
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Two recently published papers describe nuclear DNA sequences that were obtained from the same Neanderthal fossil. Our reanalyses of the data from these studies show that they are not consistent with each other and point to serious problems with the data quality in one of the studies, possibly due to modern human DNA contaminants and/or a high rate of sequencing errors.
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DNA methylation is a type of epigenetic changes that directly affects DNA. In mammals, DNA methylation is essential for fetal development and stem cell differentiation and this phenomenon essentially occurs within the CpG islands. In this study, two methods were used to study the DNA methylation profile of cow genome. In the first method, the DNA methylation profile of the differentially expres...
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Project background During the course of evolution, the human brain has undergone tremendous expansion. This has led to the development of complex neurocircuits of unmatched complexity, highly social behaviour, expanded language use and cognitive superiority. A small number of infants, however, are born with significantly smaller brains, a condition called primary microcephaly (PM). Infants with...
متن کاملRESEARCHARTICLE Sequencing and Analysis of Neanderthal Genomic DNA
Our knowledge of Neanderthals is based on a limited number of remains and artifacts from which we must make inferences about their biology, behavior, and relationship to ourselves. Here, we describe the characterization of these extinct hominids from a new perspective, based on the development of a Neanderthal metagenomic library and its high-throughput sequencing and analysis. Several lines of...
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ژورنال
عنوان ژورنال: Nature
سال: 2006
ISSN: 0028-0836,1476-4687
DOI: 10.1038/441260b